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Can You Prevent Chemotherapy Side Effects with All Natural Herbs?

Jul 24

Leucozepin

Build your immune system-increase white blood cells-

Natural ingredients-reishi mushroom & astragalus

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When someone gets diagnosed with cancer, it’s not only that person who suffers. It’s everyone around them, too! Watching someone you know and love go through chemotherapy is frustrating! You want to help but don’t know what can be done to make the other person happier and healthier. You would do anything in your power to help them get through this difficult time in their life NOW and put it in their past.

By : Dr. Donna Schwontkowski

Certainly there must be something that can be done to help your friend or loved one with cancer.

One solution is all natural herbs that can be used to strengthen the immune system and help regulate blood cell counts. These can be used as an adjunct to chemotherapy and in many cases used the same day that chemotherapy is given.

Just as drugs can affect many of the body systems, so can herbs. For example, one herb, cat’s claw from the Amazon rainforest, boosts white blood cell count and function both 34%, but also has chemical constituents in it for improving depression. In Peru, herbalists sometimes recommend placing the herb underneath the pillow and say that the next morning, a new attitude will be found.

Because of the ability of all natural herbs such as cat’s claw to affect the mind as well as the immune system, this herb is frequently found in all natural herb combination for chemotherapy patients.

Reducing Chemotherapy Side Effects Strengthens the Body

One particular herbal combination I have found recently that has been tested and researched has actions that include activating the natural killer cells that fight against cancer, relieving fatigue and boosting energy levels of those on a treatment program of chemotherapy. What a wonderful combination of benefits from something natural.

This is a major feat in itself because chemotherapy drugs are good at killing cancer cells, but during the process, normal cells are also damaged. When cells are damaged, they need to be repaired and the process can leave one feeling fatigued, weak and also susceptible to infection.

Nausea, vomiting and even pain are also common side effects. About half of chemotherapy patients report that they feel queasy even before the chemotherapy treatment session begins! It’s as if the body remembers feeling nausea from the last treatment session and is getting ready to start feeling the same thing again!

Natural herbal medicine is one of the best choices to reduce chemotherapy side effects because natural herbs often work on multiple body systems simultaneously, supporting the body functions holistically.

One proprietary formula of 15 all natural herbs has shown clinical results in an average of 7 days. The formula has a surprisingly pleasant taste and is reported by many cancer sufferers to change their condition from being bedridden to leading normal lives and even getting back to work.

The herbs included in this formula are:

Ligustrum Lucidum (fruit)

Polygonatum (root)

Poria (seed)

Codonopsis (root)

Psoralea (fruit)

Lycium (fruit)

Astragalus (root)

Dong Quai (root)

Tangerine (fruit peel)

Dendrobium (stem)

Chinese Licorice (root)

Spatholobus (stem)

Rehmannia (root)

Bai-zhu Atractylodes (root)

Reishi Mushroom (whole)

Dozens of research studies have reported that many of the all natural herbs in formulas like this are well known immune stimulators and have anti-cancer properties. They repair cellular damage, important when someone has cancer. Bai-zhu Atractylodes stimulates the two component parts of the immune system, the T cells and the B cells, producing more antibodies and more interferon and is known for its anti-cancer properties. Reishi Mushrooms promote the production of natural killer cells. Because of the actions of these all natural herbs, many cancer patients taking a combination such as this notice relief of anemia, relief of chronic fatigue, and relief from abnormal blood counts.

One of the big keys to recovering from cancer is regaining strength. Once this happens, the cancer patient feels better both physically and mentally and hope sets in.

For more info on herbal formulas that may help reduce chemotherapy side effects, see the website http://www.immuneenhance.com

Dr. Donna Schwontkowski is a master herbalist and a retired chiropractic physician. She is internationally known for her work in the field of herbs. Her website is http://www.drdonna.info

Popularity: 17% [?]

What are the side effects from the chemotherapy?

Jun 28

View the specialists from the Northern California Melanoma Center, www.melanomacenter.com, answer commonly asked questions.

Popularity: 2% [?]

High White Blood Cell Count

Jun 05

Leucozepin bestseller
Strengthens & Balances the Immune System

Secondary Benefits

  • Regulates blood cell counts
  • Boosts energy
  • Activates NK cells
  • Stimulates macrophages
  • Relieves fatigue
White Blood Cells are an important part of the body’s defense system. But too much is not always good. Read on to know why a high count of blood cells is a sign of alarm…

Blood circulates through the body providing nutrients and oxygen to all the cells in the body and similarly removes the waste products. When you go in for a complete physical test, you will probably undergo a series of tests to evaluate the composition and concentration of all the cellular components of blood. This test is known as the Complete Blood Count (CBC) and consists of tests to evaluate Red Blood Cell (RBC) count, White Blood Cell (WBC) count, the platelet count, measurement of hemoglobin, mean red cell volume and a few more.

The Complete Blood Count helps evaluate the blood and the bone marrow and is usually performed to ensure oxygen carrying capacity of the blood, identify infections, diagnose anemia and leukemia and also gauge the effect of chemotherapy and radiation therapy on blood production cells.

White Blood Cells

The white blood cells are also known as leukocytes. In the absence of any disease, they form just about 1% by volume of the total blood in the body. When produced by the bone marrow the ‘immature’ white blood cells are released into the peripheral blood and are called bands or stabs. They are destroyed in the lymphatic system 13 to 20 days after they are produced by the bone marrow.

White blood cells help fight infection through a process known as ‘phagocytosis’ wherein they surround the foreign organisms and then destroy it. Along with fighting infection, white blood cells also help produce, transport and distribute antibodies to build the body’s immune system. In case of acute infection, the white blood cells produce a substance known as the colony-stimulating factor (CSF), which stimulates the bone marrow to increase the white blood cell production. The production of the cells can be doubled within a few hours.

White Blood Cell Count

The complete blood count provides a count of the white blood cell and also an automated differential count that determines the percentage of the five types of mature white blood cells present in the human body. The five types of white blood cells are neutrophils, lympocytes, basophils, eosinophils and monocytes. Neutrophils, basophils and eosinophils have a multi-lobed nucleus. These are differentiated based on the color of the cytoplasm, size and the color of the nucleus and lastly, the size and color of the granules present in the blood cells. The white blood cell count helps provide information about various illnesses and also help monitor the patient’s recovery once treatment is started. The differential blood count indicates as to which kind of blood cells are the most affected.

The normal white blood count is between 4500 and 10000 cells per micro-liter depending on the sex and age of the individual with each type of white blood cell representing:

  • Neutrophils: 50 – 70%
  • Lympocytes: 25 – 35%
  • Basophils: 0.4 – 1%
  • Eosinophils: 1 – 3%
  • Monocytes: 4 – 6%

A high blood count (above 30000 cells per micro-liter) indicates is not a specific disease by itself but indicates infection, systemic illness, inflammation, allergy, leukemia and tissue injury caused due to burns. The count of white blood cells also increases when certain medicines like antibiotics or anti-seizure drugs. Smoking and too much of mental stress also increases the count of the white blood cells in the body. Also, once the count of white blood cell is on the higher side, the risk of cardiovascular mortality also increases. It turns into a vicious circle. On the other end, a low count of white blood cells indicates viral infections, low immunity and bone marrow failure. A severely low white blood count that is the count of less than 2500 cells per micro-liter is a cause for a critical alert and possess a high risk of sepsis.

The white blood count is an easily available, inexpensive and a reliable test which enables the doctors to arrive at better prognosis regarding the patient’s well being. However, researchers believe that a cause and effect link between the higher white blood cell count and illness has not been established and they continue to evaluate if the elevated count helps trigger a serious disease or if the cells count rises naturally after an illness.

It is very important to undergo annual physical checkups and insist on a complete blood count analysis, especially as you grow older. Diseases like cancer if detected early can be treated very easily when compared to detecting it at an advanced stage. Exercise regularly and take care of your physical and mental well being. Eat healthy and lead a long and full filling life.


By Anju Shandilya
Published: 1/2/2008

Popularity: 12% [?]

Chemotherapy Side Effects

Apr 14

By Reshma Jirage

Chemotherapy is a common treatment option for cancer. It can cause some serious side effects like anemia, hair loss, diarrhea, nausea etc. Read on to know in detail about chemotherapy side effects.
Chemotherapy is administered to treat various types of cancers. Cancer is a life-threatening disease, caused by the uncontrolled growth of abnormal cells. Cancer cells or malignant cells can spread to other parts of body through the blood and lymphatic system. There are about 100 types of cancer, such as lung cancer, breast cancer, prostate cancer, colon cancer, skin cancer, liver cancer etc. Major categories of cancer are carcinoma, sarcoma, leukemia, lymphoma and myeloma as well as cancers of the central nervous system. If cancer is diagnosed in its early stage, the chances of healing are more. The various treatment options for cancer include chemotherapy, radiation therapy and surgery. How Does Chemotherapy Work? Chemotherapy is the most common treatment method for different types of cancers. Chemotherapy involves the use of chemicals to prevent the growth of cancer cells. The drugs used in chemotherapy are known as ‘anticancer drugs’ and they destroy the malignant cells. There are different types of chemotherapy drugs, including alkylating agents, nitrosoureas, antimetabolites, anthracyclines and related medications. Chemotherapy can be administered intravenously, given orally in the form of a pill or injected into the body cavity. Generally, chemotherapy is given in cycles. Each cycle is administered every 1 to 4 weeks and there is a rest period between every chemo cycle. Chemotherapy drugs act by killing cancer cells, preventing them from spreading and slowing their growth and multiplication. Many a times, a combination chemotherapy of two or more chemo drugs may be given at a time. Some drugs restrict the effect of certain hormones in the body. Chemotherapy can be given before or after the surgery. Chemotherapy given before the surgery is called as neoadjuvant chemotherapy, which is aimed at shrinking the tumor before it is surgically removed. Chemotherapy given after the surgery is known as adjuvant chemotherapy. This therapy focuses on killing the cancer cells left after the surgery. Sometimes, chemotherapy is used in combination with radiotherapy, biological therapy or surgery. Chemotherapy Side Effects Chemotherapy is a systemic cancer treatment that can affect the entire body. Chemotherapy drugs work by destroying rapidly dividing cancer cells. But, these drugs are not able to differentiate between malignant cells and normal body cells. Malignant cells as well as some other normal cells like those in the blood, intestinal tract, nails, hair, mouth and vagina are constantly dividing. Chemotherapy drugs travel throughout the body and destroy normal, healthy cells in the bone marrow, digestive tract, hair follicle, mouth and reproductive system. Some of the chemotherapy drugs affect the cells in the lungs, heart, bladder, kidneys as well as the nervous system. This can lead to many side effects. The severity of chemotherapy side effects depends upon the type of drugs administered and the patient’s health. The side effects can be acute (short-term) or chronic (long-term) or permanent. Some common side effects of chemotherapy are constipation, diarrhea, nausea, vomiting, fatigue, hair loss and certain blood-related symptoms such as anemia. Chemotherapy can cause intestinal problems, loss of appetite, weight loss, nerve and muscle problems, sore mouth, gums and throat, dry and discolored skin, kidney and bladder irritation as well as sexuality and fertility issues. Hair loss: Temporary hair loss (alopecia) is one of the depressing side effects of chemotherapy, as it affects your appearance. Hair follicle cells are one of the rapidly dividing cells in the body. Since chemotherapy drugs cannot differentiate between these cells and malignant cells, they destroy healthy hair follicles cells, leading to hair loss. Temporary hair loss cannot be treated by the medications for hereditary hair loss. Nausea: It is one of the most common side effects of chemotherapy. It can lead to loss of appetite, constipation and dehydration. Moderate to severe nausea can also cause vomiting. Diarrhea and constipation: The cells in the intestinal lining, are among the rapidly growing normal cells that are destroyed during chemotherapy, causing diarrhea. Diarrhea during cancer treatment is also due to anxiety, stress, malnutrition or colon surgery. Diarrhea can cause stomach pain and cramping, bloating, nausea, loss of appetite and skin irritation. Some pain relievers and anticancer medications can cause constipation. These symptoms may also occur, if your diet doesn’t contain adequate amount of fibers or fluids. Allergic or hypersensitivity reaction: Chemotherapy drugs can lead to allergies or hypersensitivity reactions, triggered by the immune system response. Anaphylaxis is a severe allergic reaction, which can cause low blood pressure, shock and death. Major symptoms of allergic reactions are breathing difficulty, skin rashes, hives, flushing (redness of the face and neck), swelling of the eyelids, lips and tongue, and systemic reactions such as liver and kidney diseases. Skin problems: Chemotherapy can cause some skin problems such as skin rashes and dry skin. It can also cause flaky, cracked and itchy skin. Fatigue: Most cancer patients complain of tiredness, lack of energy and fatigue. It is due to pain, loss of appetite, lack of sleep as well as low blood counts. Fatigue due to chemotherapy appears suddenly and can last for several days, weeks or months. Mouth and throat sores: Anticancer drugs can cause irritation of the tissues of mouth and throat, resulting in bleeding. Mouth sores, also known as stomatitis or mucositis, cause swollen, red ulcers in the oral cavity. The patient is unable to talk, eat, chew or swallow due to painful ulcers. Chemotherapy can also lead to tender gums and sore throat. Nerve and muscle effects: In some cases, anticancer drugs affect the nerves, leading to peripheral neuropathy. It causes symptoms like weakness, burning, tingling, pain or numbness in the hands or feet. Some chemotherapy drugs cause weakness or soreness of muscles. Nerve and muscle-related problems can also lead to symptoms such as loss of balance, pain when walking, shaking or trembling, jaw pain, stomach pain and hearing loss. Suppressed bone marrow: Blood cells like white blood cells, red blood cells and platelets are produced in the bone marrow. Since chemotherapy targets rapidly dividing cells, it affects bone marrow cells. As a result, the production of blood cells in the bone marrow is suppressed, increasing the risk of infections. Anemia: Reduced ability of bone marrow to produce red blood cells, can cause a decrease in their number. Red blood cells are responsible for carrying oxygen to all body parts. Due to deficiency in red blood cells or anemia, body tissue is deprived of sufficient amount of oxygen. Anemia causes symptoms like fatigue, shortness of breath, dizziness, weakness and tiredness. Infection: Chemotherapy causes diminished production of white blood cells (leukopenia) in the bone marrow, leading to weakened immune system, which makes your body more vulnerable to infections. Infections are mainly due to bacteria, fungi, viruses and parasites. Some common areas for infection are mouth, throat, lungs, sinuses, skin, intestine and genital tracts. Major signs and symptoms of infection are swelling, redness and pus at the site of injury, mucus or pus in the saliva, cough, nasal drainage, sore throat, high fever, chills and a burning sensation during micturition. Bleeding or clotting problems: Due to suppressed bone marrow functioning, the number of platelets decreases. Platelets play a major role in the process of blood clotting and thus, prevent bleeding. Reduced platelet count leads to symptoms like unexpected bruising, longer bleeding after minor cuts, nosebleeds or bleeding gums, vaginal bleeding other than menstruation, hematuria, black or bloody stool, headaches and changes in vision. Flu-like symptoms: Some people experience flu-like symptoms, a few hours after the chemotherapy cycle. These symptoms include headache, nausea, tiredness, chills, slight fever, loss of appetite and muscle and joint pain. Effect on sexual organs: Chemotherapy can affect sexual organs in both men and women. Chemotherapy drugs can lower the sperm count, which may result in temporary or permanent infertility in men. Anticancer drugs can affect the ovaries and hormonal levels. This can cause menopause-like symptoms (dry vagina and hot flashes), and temporary or permanent infertility in women. In spite of these side effects, chemotherapy is one of the most effective treatment options for various types of cancer. In most cases, chemotherapy side effects disappear, after the treatment is stopped. These side effects can be prevented by taking appropriate medications, maintaining proper hygiene, intake of dietary supplements and following a healthy lifestyle that includes the right balance of a nutritious and healthy diet and regular exercises.

Popularity: 12% [?]

Scientists Enhance Immune System Attacks On Cancer

Mar 09

ScienceDaily-  Scientists have used multiple tactics to rev up both innate and adaptive immunity to enhance the body’s ability to fight cancer.

“The problem with cancer is that it becomes part of what the immune system identifies as ’self’ and there are ways the body learns to tolerate ’self’ to prevent immune attack,” says the study’s senior investigator, Linda Sherman, Ph.D., a professor in the Scripps Research Department of Immunology. “Hitting it with these new tools basically gets the immune system to pay attention to the cancer, and go after it.

She continues, “What is needed is effective and non-toxic immunotherapy for cancer patients, and we believe this work provides a foundation for that. The concepts we have shown are directly translatable to human therapy.”

Stimulating Killer T Cells

In the new study, the researchers basically used two different strategies. First, they worked out a way to force T cells—the immune system’s killer cells—to become active and grow in the presence of tumor “antigens,” the proteins on the outside of cancer cells that can stimulate an immune response. While these T cells recognize the tumor antigens, their response to them tends to be chronically weak because they are ’self’.

“We have been working for years to find ways to coax these so-called low affinity T cells to work better,” Sherman says.

In this study, the investigators tested a novel complex developed by Professor Jonathan Sprent, M.D., Ph.D., a previous member of the Scripps Research faculty who is now at the Garvan Institute in Sydney, Australia, and Scripps Research co-author, Professor Charles Surh, Ph.D. The agent combines Interleukin-2 (IL-2) with an IL-2 antibody. IL-2 is a well-known stimulator of the growth of activated T cells, and is often used to boost immune system response in human therapy; T cells have IL-2 receptors on their surface. In previous studies, Sprent and Surh found that coupling IL-2 with a specific type of IL-2 antibody allows the complex to bind better to activated T cells and produces a more robust T cell response.

“The beauty of this complex is that, as we demonstrate in this paper, it has a much greater ability to bind to low affinity T cells, which IL-2 itself cannot do very well,” says Sherman.

So, in order to jump start such an immune reaction, the researchers prime T cells by delivering this complex. When this complex binds to T cells, they grow and mature and deliver a signal to release cytotoxic granules that enter tumor cells and promote apoptosis, or cell death.

“A number of nice things begin to happen,” says Sherman. “T cell growth is promoted as well as their killing function. There is a lot of good activity.”

However, as soon as investigators withdraw the IL-2 complex, the T cells die quickly, as their growth stimulant has been removed.

The “Double Whammy”

The researchers’ second strategy, then, was to also deliver an agent known as poly(l:C) that keeps T cells surviving longer. The agent also enhances the killing power of the T cells by stimulating the innate immune system, which provides an immediate defense against invaders.

“It is this trick of really stimulating T cell proliferation and killing functions, and then keeping the T cells alive, that provides the double whammy,” Sherman says. “The T cells are hitting all their bases, and that is when we see the killing of tumors.”

The researchers tested the system in mice that spontaneously develop tumors. The researchers delivered tumor antigen, the IL2 complex, and poly(l:C) all at the same time, and demonstrated the safety and effectiveness of the strategy.

Today, there are human cancer treatments that work in the same way, but they are highly toxic, Sherman says. For example, some patients with melanoma receive melanoma antigens, infusions of T cells, and high doses of IL2, which causes a lot of harmful side effects. Since the IL-2 complex can be used at ~50-fold lower doses than IL-2 with the same efficacy, the use of complex is likely to circumvent the toxicity problem. To further rev up the immune response, patients sometimes also receive whole body irradiation, which produces widespread inflammation.

“We think we can provide two very safe ways to hit these same bases,” Sherman says.

However, more research needs to be done before human studies can begin, including finding an antibody to human IL-2 that works in the same way.

This research is published in an Early Edition issue of the Proceedings of the National Academy of Sciences (PNAS) published online on October 20, 2008.

In addition to Sherman and Surh, study co-authors were Gregory Verdeil, Ph.D., and Kristi Marquardt of The Scripps Research Institute.

The study was funded by the National Institutes of Health.


Journal reference:

1. Verdeil et al. Adjuvants targeting innate and adaptive immunity synergize to enhance tumor immunotherapy. Proceedings of the National Academy of Sciences, September 17, 2008; DOI: 10.1073/pnas.0805054105

Popularity: 7% [?]

The Place of All Natural Chinese Herbs in Cancer Treatment

Feb 01

By Dr. Donna Schwontkowski

Medical philosophy is vastly different than all natural herbal therapy. Medical doctors are aggressive in their attack on cancer and try to burn the cancer out, cut it out, or kill it with potent drugs. Herbal philosophy is based on the support of the body’s natural defenses and working with the body until any illness is gone. Both philosophies have their triumphs and challenges. In many people’s minds, the big question is where do all natural Chinese herbs fit into the grand scheme of cancer treatment?

Why Not Mix Both Philosophies?

Many alternative health practitioners and even medical physicians now have decided that both philosophies can be incorporated together and result in a more successful outcome for patients with cancer, especially those on chemotherapy treatment. In the last few decades, clinical research studies have proven that it is indeed possible to  combine medical therapy with all natural Chinese herbs.

For example, synthetic IL-2 is often used as a treatment modality by the medical profession for patients with colorectal cancer, lymphoma, melanoma, and kidney cancer. The chemotherapy drug is extremely toxic and can cause serious side effects. The herb Astragalus was given to patients with colorectal cancer. When researchers and doctors combined their efforts and administered the all natural Chinese herb Astragalus to patients receiving synthetic IL-2, the white blood cells of patients became faster and more efficient. The drug’s effectiveness was enhanced, proving that a chemotherapy natural solution mixture could work, that all natural Chinese herbs do indeed have a place in chemotherapy treatment.

Studies show that Astragalus helps in cancer cases by increasing killer cells. Astragalus also helps offset immune damage from numerous drugs. Astragalus protects the immune system, increases the metabolic rate and increases energy levels. All these functions can only aid a chemotherapy patient.

Researchers frequently comment on the use of Astragalus to alleviate the toxic side effects of chemotherapeutic drugs. In the peer-reviewed journal, Carcinogenesis, June of 2007, researchers M.M. Tin et al reported that Astragalus inhibited cell growth and promoted the death of cancer cells. They also found that Astragalus reduced the size of tumors without causing death and without causing a drop in body weight in studies on mice. The researchers concluded that Astragalus could be an effective chemotherapeutic agent in colon cancer treatment and used as an adjuvant in combination with other orthodox chemotherapeutic drugs to reduce the side effects of chemotherapy compounds.

In another study, patients with small cell lung cancer used traditional chemotherapeutic drugs like vincristine, cyclophosphamide and carmustine and researchers added the all natural Chinese herbs ginseng and Astragalus to the therapy. The survival rate increased to as long as 17 years in some of the patients! Again, this proved that a chemotherapy natural solution mixture of treatment could work.

Glycyrrhiza glabra, of licorice, is also another Chinese herb that activates immune cells in human subjects. The Journal of Phytotherapy Research reported on a study in August 2006 where immune cell function was enhanced within 24 hours of ingesting licorice and also Astragalus and Echinacea. CD4 and CD8 T cell counts increased and continued for at least seven days. When the all natural Chinese herbs licorice and Astragalus along with Echinacea were used together, another immune cell function was improved, that of CD69 expression.

There are plenty of other studies that show that all natural Chinese herbs can be used as a chemotherapy natural solution. What we are seeing is that using the chemotherapy drugs by themselves can almost assure one of toxic side effects to come, but using them with the all natural Chinese herbs, the chemotherapy treatment can be endured better and with a higher quality of life.

For more info on herbs that help chemotherapy fatigue and other side effects, see http://www.immuneenhance.com

For more info on articles on health, see http://www.drdonna.info

Article Source: http://EzineArticles.com/?expert=Dr._Donna_Schwontkowski http://EzineArticles.com/?The-Place-of-All-Natural-Chinese-Herbs-in-Cancer-Treatment&id=1070074

Popularity: 4% [?]

Side Effects of Chemotherapy

Jan 15

leucozepin

Leucozepin bestseller
Strengthen Immune System: contains Astragalus

Secondary Benefits

  • Regulates blood cell counts
  • Boosts energy
  • Activates NK cells
  • Stimulates macrophages
  • Relieves fatigue
You can imagine a situation where apart from the anguish of having cancer, patients receiving chemotherapy for it find that they also have to deal with the side effects of the treatment which can be fairly devastating.Fortunately like most things in life, understanding the side effects and the causes for it is an excellent place to start in alleviating the suffering. And understanding the basic reason for the side effects of chemotherapy is not as difficult as most people think it is. All you need to grasp is what chemotherapy does to the body. The whole idea behind chemotherapy is to kill cancer cells. However in the course of destroying the deadly cancerous cells the treatment also damages other normal cells. The unavoidable harming of these normal cells is what causes the side effects associated with chemotherapy.

The cells that are usually affected include bone marrow blood cells, cells of hair follicles, cells lining the digestive tract and cells lining the reproductive tract. Looking at this list of the cells that are usually destroyed, one can start to recognize some the ailments that cause so much suffering to people going through chemotherapy treatment. Now you understand exactly why people end up losing their hair for instance. This is as a result of the cells of hair follicles being damaged by chemotherapy.

Bone marrow cells being affected during cancer treatment is one of the most common causes of many of the side effects of chemotherapy. Bone marrow is a thick liquid in the inner part of some bones which usually produces white blood cells. This damage leads to low white blood cell counts or what doctors call neutrophil. The kind of signs and symptoms that follow include fever, sore throat, coughs, shortness of breath, nasal congestion, burning during urination, shaking chills as well as redness, swelling, pain, and warmth at the site of an injury amongst other symptoms.

Usually because of the high risk of infections, doctors may need to delay further chemotherapy doses. These are some of the factors that cause so much suffering amongst cancer patients.

Fortunately new research and clinical trials offers some hope in greatly alleviating problems related to cancer and cancer treatment. For example natural herbal medicines have been used for hundreds of years and now regularly complement mainstream care in managing symptoms, boosting the immune system and greatly enhancing the quality of life. Actually many cancer patients going through chemotherapy have reported impressive results from natural herbal medicine in addressing the side effects of chemotherapy.

Get more information on the Side Effects Of Chemotherapy

Popularity: 6% [?]

Low White Blood Cell Count

Dec 02

White blood cells are an important part of the human body’s immune system. Their count decreases due to different causes and leads to various health problems. Here is some useful information about low white blood cell count.

Blood is a liquid connective tissue, composed of plasma and different types of cells. Blood plays an important role in supplying oxygen and nutrients to all the body organs. Its two major functions are: 1. Transportation of oxygen and carbon dioxide, ions, food molecules such as lipids, glucose and amino acids, hormones and wastes 2. Protection of the body against infection and foreign bodies. It consists of different types of cells such as Red Blood Cells (RBCs), White Blood Cells (WBCs) and Platelets/thrombocytes.

What are White Blood Cells?

White blood cells or leukocytes are the cells of the immune system. They protect the body against the foreign materials and infections. They are divided into two categories such as granulocytes and agranulocytes. The granulocytes are of three types such as neutrophils, eosinophils and basophils. Lymphocytes and monocytes are the agranulocytes. The normal count of white blood cells is 4,000-10,000/mm3. They have a short lifespan, ranging from a few days to a few weeks. These cells offer defensive properties to blood in order to fight against the infections and the invading foreign bodies such as bacteria and viruses. If number of leukocytes increases than the normal count, the condition is known as leukemia. If the white blood cell count is below normal, it is known as leukopenia. There may be decrease in individual leukocyte percentage, e.g. neutropenia, i.e., a decrease in number of neutrophils. The reduction of all types of white blood cells is known as panleukopenia.


Causes of Low White Blood Cell Count

An abnormal low white blood cell count is associated with a number of causes and medical conditions. Some of the causes of leukopenia are aplastic anemia, chemotherapy, autoimmune diseases such as lupus, chemotherapy, radiotherapy, liver diseases, spleen diseases, a deficiency of vitamins and minerals such as zinc and copper, and autoimmune diseases. Certain infections such as viral infections can cause low white blood cell count. Some of the medications including chemotherapy drugs, some of the antibiotics and immunosuppressive drugs also lead to leukopenia. Certain bone marrow diseases such as myelodysplastic syndrome or leukemia reduce the white blood cell count. Sometimes, the exact cause of leukopenia is not known, it is referred to as idiopathic.

Symptoms of Low White Blood Cell Count

When the white blood cell count is reduced, the body tends to catch the infection easily. Fever is the first indication of infection. The gastrointestinal system and bladder are the areas of potential infection. Hence, watch for the symptoms such as diarrhea, stomach cramps, rectal bleeding and urination problems. Mouth sores, sore gums or canker sores also indicate the decreased white blood cell count. Sore throat, cough, headache and sneezing are the signs of lung or sinus infection. Whenever you notice these symptoms, consult the doctor and if needed, have the blood test to determine the white cell count.

Effects of Low White Blood Cell Count

A reduction in white blood cell count leads to weakened immune system, as these cells are an integral part of the immune system. A person with low white blood cell count is at higher risk of bacterial, fungal and viral infections due to a compromised immune system. The infections of gastrointestinal system, lungs, throat and bladder are are some typical examples of low white blood cell count infections.

Treatment for Low White blood Cell Count

When you notice the symptoms of infection due to leukopenia, you should immediately consult the doctor. Complete blood count and absolute neutrophil count are the commonly recommended tests for the diagnosis of leukopenia. Sometimes, a bone marrow examination is suggested by the doctor for an accurate diagnosis.

The medications used to treat leukopenia are known as ‘growth factors’. They consist of cytokines, which stimulates the bone marrow to produce more number of white cells. Two commonly prescribed drugs are filgrastim and pegfilgrastim. Some antimicrobial medications and antibiotics are also prescribed by the doctors to treat the infections. If low white blood cell count is due to the chemotherapy drugs, it is advised to delay the chemotherapy treatment or reduce the chemotherapy dose. Have a balanced and nutritious diet.

Precautions for People with Low White Blood Cell Count

People with low white blood cell count need to take some precautions in order to minimize the risk of infection. Hands are the means of a spread of infections. Hence, wash your hands frequently with soap and plenty of water. Dry and chapped skin is more prone to infection. In order to keep your skin moisturized, use a body lotion after each wash. Try to avoid large crowds in order to avoid any contact with the infected and sick people. Stay away from the things that can cause cuts or wounds on your skin. Wear gloves and mask whenever possible. If you have any kind of wound or trauma, get it treated immediately.


By Reshma Jirage
Published:
6/27/2008

Popularity: 6% [?]

Anemia Triples Risk of Local Recurrence in Breast Cancer Patients

Apr 25

By Nicholas Mulcahy, HealthDay  -

Breast cancer patients who develop anemia during chemotherapy face almost three times the risk of a recurrence in the same area of the affected breast, new research suggests.

The Austrian study was a re-analysis of information from a clinical trial that took place in the 1990s. Importantly, the findings also indicated that anemia did alter overall survival or significantly increase the risk of cancer occurring in a patient’s other breast or spreading elsewhere in the body. Anemia, a common side effect of chemotherapy, is a low red blood cell count that can cause fatigue and reduced quality of life.

“This study is definitely not aimed at changing current practice,” said study author Dr. Peter Dubsky, of the Medical University of Vienna. “This is a retrospective analysis that has yielded quite controversial data. The conclusion from our study is aimed at experimental and clinical oncologic research. Anemia is associated with a high likelihood of tumor hypoxia [too little oxygen in the blood].”

The chemotherapy used in the study was a combination of cyclophosphamide, methotrexate and 5-fluorouracil (CMF). The problems of anemia and related local recurrence are probably not limited to just this form of chemotherapy, noted Dr. Douglas Yee, director of the University of Minnesota Cancer Center. “I think this effect would be seen with any chemotherapy.”

CMF is no longer commonly used in the treatment of breast cancer and has been replaced by other forms of chemotherapy such as taxanes, added Dr. Barry C. Lembersky, a clinical associate professor of medicine at the University of Pittsburgh School of Medicine. Also, there is a trend in breast cancer treatment to use chemotherapy less often, he said.

“Nowadays, there is a more selective use of chemotherapy, which tends to be used when a tumor is not stimulated by estrogen, lymph nodes are involved, or the genetic/clinical profile is suited for chemotherapy,” he explained.

In the Austrian study, CMF therapy was used as an additional treatment in 424 patients who were premenopausal and who underwent surgery as their main treatment for early-stage breast cancer. All had estrogen receptor-positive malignancies. The findings were published in the April 1 issue of Clinical Cancer Research.

The surgery was either a breast-conserving lumpectomy, which required additional radiation, or a modified radical mastectomy, for which radiation was optional. The radiation was given in the middle of chemotherapy treatment process, which is now an outdated method, Yee noted. “We tend not to do this kind of sandwich technique anymore,” he explained.

After an average follow-up of 61 months, 39 local relapses occurred among the 424 women: 6.9 percent in patients without anemia and 19.5 percent in patients with anemia. The five-year rates of local relapse were 8.2 percent among patients without anemia and 19.6 percent among patients with anemia.

In addition to anemia, two other factors — an older age at diagnosis and positive lymph node status — significantly increased the risk of a local recurrence of breast cancer. According to an analysis of the range of factors examined in the study, patients with anemia had a 2.96-fold increased relative risk of a local recurrence.

Since the Austrian research was conducted, the treatment of anemia in breast cancer patients has become controversial, Lembersky noted.

“Erythropoietin-stimulating agents are indicated for use by the FDA [U.S. Food and Drug Administration] when red blood cell counts are too low,” he said. “However, there is now controversy about their use due to the possible increase in tumor growth in breast cancer.”

Dubsky agreed.

“I am sure you are aware of the recent pitfalls in the use of erythropoiesis-stimulating agents (ESAs),” he said. “Given this context, we should start discussing anemia more in the context of tumor hypoxia and look for targets that are distinct from erythropoiesis.”

More informationHere’s more on the treatment of early-stage breast cancer.

content by:

Healthday

SOURCES: Peter Dubsky, M.D., Department of Surgery, Medical University of Vienna, Austria; Douglas Yee, M.D., director, University of Minnesota Cancer Center, Minneapolis; Barry C. Lembersky, M.D., clinical associate professor, medicine, University of Pittsburgh School of Medicine; April 1, 2008, Clinical Cancer Research

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Traditional Chinese Medicinal Herbs May Help Women With Breast Cancer

Apr 25

ScienceDaily — Using Chinese herbs either alone or in conjunction with chemotherapy may help protect a breast cancer patient’s bone marrow and immune system, as well as improving the woman’s overall quality of life.

Sixty per cent of women undergoing chemotherapy for breast cancer experience a range of significant short term side effects. These include nausea, vomiting and fatigue, as well as inflammation of the gut lining, decreased numbers of red and white blood cells and decreased numbers of blood platelets.

Chinese medicinal herbs include mixtures of herbal compounds or extracts from herbs, and they are prescribed to counteract the side effects of chemotherapy. This Cochrane Systematic Review set out to see if there is conventional evidence indicating that these medicines are safe and whether there is evidence that the medicines are effective.

The researchers identified seven randomised studies involving 542 patients with breast cancer. By analysing these data, the researchers concluded that there was no evidence that the Chinese medicinal herbal treatment caused harm, and some evidence that it might reduce side effects.

“Further trials are needed before the effects of traditional Chinese medicines for people with breast cancer can be evaluated with any real confidence,” says Assistant Professor Jing Li, who works at the Chinese Cochrane Centre in Chengdu, China.

John Wiley & Sons, Inc. (2007, April 18). Traditional Chinese Medicinal Herbs May Help Women With Breast Cancer. ScienceDaily. Retrieved December 4, 2007.

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