ScienceDaily
A new study suggests that sleep problems lead to increased pain and fatigue in cancer patients. The results indicate that interventions aimed at trouble sleeping would be expected to improve both pain and fatigue in this patient population.
Results show that more than half the sample reported having trouble sleeping, with 26 percent reporting moderate or severe trouble sleeping. Compared with patients who reported no trouble sleeping, patients with moderate to severe trouble sleeping reported significantly more fatigue, pain and depressed mood. Using structural equation modeling analysis to evaluate causal relations and directions of effect, the best-fitting model indicates that trouble sleeping led to increased ratings of pain.
According to the authors, the relationship between pain and sleep often has been assumed to be reciprocal. In the present study, however, a model of reciprocal causation could not be fit to the data, and models in which pain caused trouble sleeping did not fit as well as the model in which trouble sleeping caused pain.
“We believed we would find a bi-directional relationship between insomnia and pain, but instead found that trouble sleeping was more likely a cause, rather than a consequence, of pain in patients with cancer,” said lead author Edward J. Stepanski, chief operational officer at the Accelerated Community Oncology Research Network in Memphis, Tenn.
The study included demographic, clinical and patient-reported outcomes data from 11,445 cancer patients undergoing treatment at the West Clinic, a large community oncology practice in Memphis. Participants had an average age of 61.5 years, and 74 percent were female. Breast cancer was the most common form of cancer, and about 25 percent of study subjects had received chemotherapy in the last 30 days. Increases in depressed mood also led to increased ratings of pain.
Younger age and recent administration of chemotherapy were both associated with increased trouble sleeping. According to the authors, younger patients often receive more aggressive chemotherapy than older patients; therefore, younger patients may be exposed to more treatment-related toxicity.
Stepanski stated that several studies have shown that cognitive behavioral therapy (CBT) improves sleep in cancer patients who have insomnia. He believes that this type of intervention may decrease patients’ pain and fatigue by improving their sleep.

Adapted from materials provided by American Academy of Sleep Medicine, via EurekAlert!, a service of AAAS.
Journal Reference:
1.The Relation of Trouble Sleeping, Depressed Mood, Pain, and Fatigue in Patients with Cancer. Journal of Clinical Sleep Medicine, April 15, 2009

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Liz Weiss, MS, RD is a dietitian and co-author of THE MOMS’ GUIDE TO MEAL MAKEOVERS and hosts this segment.

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Health and Nutritional Supplements, You Need Both

By: Tan Kim Kia

Health is the greatest treasure a man can have.

There are several factors that influence our health. Among them we find the pollution, stress, inadequate nutrition. All these factors are hurtful to our body.

Did you know that in a whole year we consume over four kilos and a half to five kilos of poisonous substances present in our food?

If not eliminated, these substances create a chaotic movement of our body cells and generate a favorable ground for the action of free radicals. These free radicals generate a great diversity of cancer forms.

Health depends on an adequate diet too. “Scientific evidence in support of the health benefits of nutritional supplements has grown dramatically in recent years,” said Jeffrey Blumberg, Ph.D., a professor in the School of Nutrition Science and Policy at Tufts University in Boston. “We must now work to translate this knowledge to health care providers, policy makers and consumers so the simple actions people can take to promote their health and prevent disease can be more fully realized. The impact of a rational use of dietary supplements can also help reduce health care costs which escalate every year as our population grows older.

Symptoms

Many problems such as : lack of energy, insomnia, headaches, depression, mood swings, anxiety, easy bruising, bleeding gums, slow wound healing etc. can be traced directly to deficiencies in specific vitamins and minerals.

Circumstances

Because of the methods applied nowadays in agriculture, which destroy the natural mineral substances, we cannot be sure that the agricultural products ensure us the necessary vitamins and minerals. Although all people should try to have healthy and balanced diet, few in reality do.

Nutritional Supplements to bridge your nutrition gaps

More and more people try the nutritional supplements as a way to combat the nutritional deficiencies and to ensure the necessary of vital nutrients for maintaining the quality of their life. Before you start taking nutritional supplements you must know a few things about them.

Nutritional supplements represent a support to our body. The nutritional supplements clean the human body and restore the deficiencies present inside. While taken constantly, nutritional supplements promote good health and help prevent disease. Nutritional supplements represent a good thing that we need . Here are a few things that you might consider before taking nutritional supplements:

1. Everybody can consume nutritional supplement and mostly if is diagnosed with a nutritional deficiency.

2. You must find out if you have a nutritional deficiency.

3. Ask your physician if it is safe for you to take nutritional supplements.

4. Does this supplement interacts with any drug or food you are consuming?

5. If you want to know more you can read about it or you can find more information at nutritional supplements guide from the Internet.

Quality

Regarding their quality, the nutritional supplements must be natural, easy to assimilate, must have a high nutritional value, must come from ecologically non-polluted areas and must be certified.

On the market are thousands of dietary supplements. Great companies fight for a place on the market. Each of them offers a diversity of products. These products seem to bring the same benefits to our body but they are in fact very different one from another. The difference is obvious when you read the label and you see the ingredients. The ingredients are the ones which make the products so valuable.

Research

The nutritional supplements are usually obtained after a period of research.

The research services work hard in order to offer us good products having great and rapid effects. It would be good for you when you choose to take nutritional supplements to inform upon the company which produces the products. If it is a world leadership or if it is among the greatest in the world than you may decide to consume the products it proposes to you. They are first tested over and over again and are only then offered to the public.

So we must be very careful when choosing nutritional supplements and do not forget to consult your physician!

About the Author:

Allan Tan Kim Kia is an nutrition scholar and author of Best Vitamin Supplements Guide who provides tips and advice how to choose and where to buy best vitamin supplements online. http://www.best-vitamin-supplements-guide.com

Printed From: http://www.articlesbase.com/nutrition-articles/health-and-nutritional-supplements-you-need-both-83822.html

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One Virus Particle Is Enough To Cause Infectious Disease

ScienceDaily (Mar. 14, 2009) — Can exposure to a single virus particle lead to infection or disease? Until now, solid proof has been lacking. Experimental research with insect larvae at Wageningen University and Simon Fraser University in Canada has shown that one virus particle is theoretically enough to cause infection and subsequent disease.

A virus population is usually composed of a collection of variants of virus particles. In order to  investigate whether virus particles (virions) can cause an infection independently from each other, and therefore individually, the researchers set up an experiment with two ‘marked’ virus variants. They exposed a population of hosts (caterpillars) to both variants.

The experiment showed that exposure to a low dosage of virus particles resulted in a small number host infections (20%). The majority of these hosts (86%) turned out to be infected by a single virus genotype. In contrast, exposure to a high dosage of virus particles resulted in virtually all the hosts (99%) becoming infected, where most of the hosts were infected by both types of virus. Only 14% were infected by only one of the two variants.

Based on the assumption that every virus particle operates independently from all other virus particles, the researchers set up a probability model. This model predicts how many virus particles have caused an infection and how many different virus genotypes are present in infected hosts, such as plants, insects or people. The results of the infection experiment with the susceptible insects are in agreement with the model predictions. From this it can be derived that the virus particles have an independent effect, and that a single virus particle can indeed cause infection and/or disease.

If there are few virus particles that lead to an infection, the number of virus particles determines the degree of diversity that can be present within the host. This is an important finding because the interactions between virus variants, such as competition and exchanging genetic information, determine the progression of disease and the evolution of the virus.

Until now, it was unclear whether a virus must be seen as an individual that can infect a host independently, or whether a cloud of viruses ‘cooperates’ to cause an infection. It is not yet known if the viruses that affect people can also act individually, but this research shows that it is possible.

The researchers recently published this finding in the Proceedings of the Royal Society B.

Journal reference:

1. Mark P Zwart, Lia Hemerik, Jenny S Cory, J. Arjan G.M de Visser, Felix J.J.A Bianchi, Monique M Van Oers, Just M Vlak, Rolf F Hoekstra, and Wopke Van der Werf. An experimental test of the independent action hypothesis in virus%u2013insect pathosystems. Proc. R. Soc. B, 2009; DOI: 10.1098/rspb.2009.0064..Adapted from materials provided by Wageningen University and Research Centre.

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ScienceDaily (May 5, 2009) — As the swine flu continues its global spread, researchers from the Children’s Hospital of Philadelphia have discovered important clues about why influenza is more severe in some people than it is in others.

In their research study published online in the Journal of Leukocyte Biology, the scientists show that the influenza virus can actually paralyze the immune systems of otherwise healthy individuals, leading to severe secondary bacterial infections, such as pneumonia. Furthermore, this immunological paralysis can be long-lived, which is important to know when developing treatment strategies to combat the virus.

According to Kathleen Sullivan, M.D., Ph.D., the senior researcher involved in the study and Chief of the Division of Allergy and Immunology at the Children’s Hospital of Philadelphia, “We have a very limited understanding of why some people who get influenza simply have a bad cold and other people become very sick and even die. The results of this study give us a much better sense of the mechanisms underlying bacterial infections arising on top of the viral infection.”

Sullivan and colleagues recruited pediatric patients with severe influenza and examined the level of cytokines, which serve as the first line initiators of immune response, in the blood plasma. Although they found elevated levels of cytokines, they also found a decreased response of toll-like receptors, which activate immune cell responses as a result of invading microbes. This suggests that the diminished response of these receptors may be responsible for the paralysis of the immune system, leading to secondary bacterial infections.

The influenza patients were compared with patients with moderate influenza, respiratory syncytial virus, and a control group of healthy individuals. The immune paralysis appeared to be specifically a result of influenza infection and was not seen in patients with respiratory syncytial virus. This process might explain why one quarter of children who die from influenza, die from a bacterial infection occurring on top of the virus.

“Despite major medical advances since the devastating flu outbreak of 1918 and 1919, influenza virus infection remains a very serious threat,” said John Wherry, Ph.D., Deputy Editor of the Journal of Leukocyte Biology, “and the current swine flu outbreak is a grim reminder of this fact. The work by Dr. Sullivan and colleagues brings us a step closer to understanding exactly what goes wrong in some people who get the flu, so, ultimately, physicians can develop more effective treatment strategies.”

Journal reference:

1. Meredith L. Heltzer, Susan E. Coffin, Kelly Maurer, Asen Bagashev, Zhe Zhang, Jordan S. Orange, and Kathleen E. Sullivan. Immune dysregulation in severe influenza. Journal of Leukocyte Biology, 2009; DOI: 10.1189/jlb.1108710

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When someone gets diagnosed with cancer, it’s not only that person who suffers. It’s everyone around them, too! Watching someone you know and love go through chemotherapy is frustrating! You want to help but don’t know what can be done to make the other person happier and healthier. You would do anything in your power to help them get through this difficult time in their life NOW and put it in their past.

By : Dr. Donna Schwontkowski

Certainly there must be something that can be done to help your friend or loved one with cancer.

One solution is all natural herbs that can be used to strengthen the immune system and help regulate blood cell counts. These can be used as an adjunct to chemotherapy and in many cases used the same day that chemotherapy is given.

Just as drugs can affect many of the body systems, so can herbs. For example, one herb, cat’s claw from the Amazon rainforest, boosts white blood cell count and function both 34%, but also has chemical constituents in it for improving depression. In Peru, herbalists sometimes recommend placing the herb underneath the pillow and say that the next morning, a new attitude will be found.

Because of the ability of all natural herbs such as cat’s claw to affect the mind as well as the immune system, this herb is frequently found in all natural herb combination for chemotherapy patients.

Reducing Chemotherapy Side Effects Strengthens the Body

One particular herbal combination I have found recently that has been tested and researched has actions that include activating the natural killer cells that fight against cancer, relieving fatigue and boosting energy levels of those on a treatment program of chemotherapy. What a wonderful combination of benefits from something natural.

This is a major feat in itself because chemotherapy drugs are good at killing cancer cells, but during the process, normal cells are also damaged. When cells are damaged, they need to be repaired and the process can leave one feeling fatigued, weak and also susceptible to infection.

Nausea, vomiting and even pain are also common side effects. About half of chemotherapy patients report that they feel queasy even before the chemotherapy treatment session begins! It’s as if the body remembers feeling nausea from the last treatment session and is getting ready to start feeling the same thing again!

Natural herbal medicine is one of the best choices to reduce chemotherapy side effects because natural herbs often work on multiple body systems simultaneously, supporting the body functions holistically.

One proprietary formula of 15 all natural herbs has shown clinical results in an average of 7 days. The formula has a surprisingly pleasant taste and is reported by many cancer sufferers to change their condition from being bedridden to leading normal lives and even getting back to work.

The herbs included in this formula are:

Ligustrum Lucidum (fruit)

Polygonatum (root)

Poria (seed)

Codonopsis (root)

Psoralea (fruit)

Lycium (fruit)

Astragalus (root)

Dong Quai (root)

Tangerine (fruit peel)

Dendrobium (stem)

Chinese Licorice (root)

Spatholobus (stem)

Rehmannia (root)

Bai-zhu Atractylodes (root)

Reishi Mushroom (whole)

Dozens of research studies have reported that many of the all natural herbs in formulas like this are well known immune stimulators and have anti-cancer properties. They repair cellular damage, important when someone has cancer. Bai-zhu Atractylodes stimulates the two component parts of the immune system, the T cells and the B cells, producing more antibodies and more interferon and is known for its anti-cancer properties. Reishi Mushrooms promote the production of natural killer cells. Because of the actions of these all natural herbs, many cancer patients taking a combination such as this notice relief of anemia, relief of chronic fatigue, and relief from abnormal blood counts.

One of the big keys to recovering from cancer is regaining strength. Once this happens, the cancer patient feels better both physically and mentally and hope sets in.

For more info on herbal formulas that may help reduce chemotherapy side effects, see the website http://www.immuneenhance.com

Dr. Donna Schwontkowski is a master herbalist and a retired chiropractic physician. She is internationally known for her work in the field of herbs. Her website is http://www.drdonna.info

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• Strengthen the immune system
• Helps individuals speed recovery from illnesses
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Influenza And Bacterial Pneumonia Make For Harmful Super-infection

ScienceDaily

Influenza, or flu, is an unpleasant affair with fever, cough, as well as head and body ache.
When this illness is further complicated by a
bacterialpneumonia, a harmful super-infection develops. Until now, researchers thought
that the flu facilitates an infection with pneumonia bacteria because it leads
to a decrease of immune cells in the blood and thus impairs the body's
defenses.
A joint venture from researchers from the Helmholtz-Centre for Infection
Research (HZI) in Braunschweig, the Otto-von-Guericke-University in Magdeburg,
and the Karolinska institute in Sweden have taken an in-depth look at the
connection between flu infection and pneumonia. Their results have disproven a
common theory about flu-like pneumonia.

Some viral infections trigger a decrease of immune cells in the blood – a
so-called "lymphopenia". The reasons behind it and whether this is
the case with influenza are unknown. To investigate the latter, HZI researchers
infected mice with flu viruses and measured the amount of immune cells in the
animal's blood every day. Some days later, flu-infected mice received a dosage
of pneumonia bacteria usually harmless for healthy mice. While the flu-infected
mice did develop a superinfection & subsequently died, surprisingly, they
were not suffering from lymphopenia. The healthy, non-flu-infected mice
defeated the bacteria successfully and recovered.

To discover whether a lack of immune cells encourages an infection with
pneumonia bacteria in general, an artificial drug-induced lymphopenia was
established in the mice. Without infecting these lymphopenic mice with flu
viruses, they received pneumonia bacteria. Despite a severe lack of immune
cells, the mice recovered completely.

With these results, the researchers could show that influenza facilitates
and intensifies an infection from pneumonia bacteria, while disproving the
common idea that this is caused by a lack of immune cells. "This result
was an enormous surprise for us because it directly contradicts widespread
assumptions", says Sabine Stegemann, researcher in the groups "Immune
regulation" at the HZI and "Molecular Immunology" at the
Otto-von-Guericke-University in Magdeburg.

"Now we want to understand the reasons for the increased
susceptibility", says Matthias Gunzer, head of the group in Magdeburg.
"It could be interplay of weakened mucous membranes and scavenger cells
that induce ideal conditions for pneumonia bacteria to create a deadly lung infection.
Another reason may be a reaction of the host immune system: It disables
hyperactive flu-fighting immune cells to inhibit destruction of healthy lung
tissue. "The immune system keeps itself under control and that makes it
easy for pneumonia bacteria to infect the lung", says Gunzer.
Increased Susceptibility for Superinfection with Streptococcus pneumoniae
during Influenza Virus Infection Is Not Caused by TLR7-Mediated Lymphopenia 2009; 

Adapted from materials provided by Helmholtz Association of German Research Centres,
via EurekAlert!, a service of AAAS.

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The long-term side effects from chemotherapy cancer treatments can include a suppressed immune system, weight loss, hair loss and increased risk of developing other cancers. Find out how many chemotherapy side effects will go away with time with insight from a doctor in this free video on chemotherapy and cancer treatments.

Expert: Dr. David Cathcart
Bio: Dr. David Cathcart has been an occupational medicine physician at Heartland Regional Medical Center in St. Joseph, Mo. for more than 20 years.
Filmmaker: Johnny Cathcart

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Good nutrition for reducing chemotherapy treatment side effects includes eating several small meals, sticking with bland foods and avoiding liquids with meals. Ask a doctor about vitamin or mineral supplements that may help with chemotherapy using advice from a doctor in this free video on chemotherapy and cancer treatments.

Expert: Dr. David Cathcart
Bio: Dr. David Cathcart has been an occupational medicine physician at Heartland Regional Medical Center in St. Joseph, Mo. for more than 20 years.
Filmmaker: Johnny Cathcart

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